38 PERIPHERAL ENDOTHELIAL FUNCTION AND CARDIOPULMONARY FUNCTION IN PATIENTS AFFECTED BY PULMONRY HYPERTENSION

Abstract Background Pulmonary arterial hypertension (PAH) is a progressive and severe rare disease. It pulmonary vasculature obstructive disease that leads to right heart failure death. circulation dysfunction endotelial characterized by vasoconstriction proliferation. Aim of study search possible correlations between peripheral endothelian function cardiopulmonary in patients with suspect PAH. Materials Between February 2021 May 2022, consecutive PAH underwent assessment FMD before catheterization exercise testing. Results 46 (22 male, 67,9 ± 10,4 years old) were enrolled the study. The following found stress-resting absolute difference % radial diameter: ramp (r: 0,69; p: 0,003 r: 0,54; 0,028, respectively), Watt_AT 0,63; 0,01 0,03, respectively) WATT_peak 0,64, 0,009). Conclusions endothelial may be related funtional capacity affected hypertension.